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Vulnerable relationships between affective and cognition disorders and type 2 diabetes mellitus – results of a mapping review


Authors: D. Obšilová 1;  M. Bretšnajdrová 2;  K. Ivanová 2
Authors‘ workplace: Univerzita Palackého v Olomouci, Lékařská fakulta ;  Ústav veřejného zdravotnictví, Přednostka: prof. MUDr. Dagmar Horáková, Ph. D. 1;  Fakultní nemocnice Olomouc, II. interní klinika - gastroenterologická a geriatrická, Přednosta: doc. MUDr. Ondřej Urban, Ph. D. 2
Published in: Prakt. Lék. 2023; 103(3): 138-145
Category: Of different specialties

Overview

Background: The prevalence of type 2 diabetes mellitus (DM2) is increasing worldwide. With more than 430 million cases, diabetes ranks among the most common non-infectious diseases in the world. The incidence of the disease is rising sharply in people over 65 years of age. Natural involutional processes and comorbidities in the elderly can lead to the occurrence of the geriatric syndrome, which significantly affects the therapy, prognosis and quality of life of the patient. Recent research shows that DM2 can play a significant role in the development and prognosis of geriatric syndromes. Studies suggest reciprocal relationships in both etiology and genesis between DM2, depression, and cognitive impairment.

Aim and purpose of the message: The aim of the presentation is to reveal, with a mapping review, the repeated findings of the connection between DM2, cognitive disorders and depression in relation to the genesis and consequences of the disease.

Methods: The methodology for collecting and processing data from professional articles was chosen as a mapping review – an analysis of scientific papers from the defined period 2009–2019 and a graphical representation of their results into systematic units with a representation of mutual relationships. The presentation will also include an overview table of the studies, including their short outputs and localization.

Results: The mapping review revealed repeated findings of the connection between DM2 and depression in relation to the genesis and consequences of the disease, while both mentioned diseases can then lead to cognitive disorders. An unrecognized cognitive disorder can, on the other hand, complicate DM2 therapy and lead to decompensation of this disease.

Conclusion: Unraveling the interrelationships between DM2 and the mentioned geriatric syndromes with the aim of effective treatment of depression and cognitive deficit leads to improvement of patient compliance and adherence as well as the treatment of DM2. This form of secondary prevention could significantly increase the quality of life of seniors.

Keywords:

geriatric syndromes – diabetes mellitus – mutual reciprocity


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