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Non-neoplastic portal vein thrombosis


Authors: D. Kamenář;  J. Špičák
Authors‘ workplace: Přednosta: prof. MUDr. Julius Špičák, CSc. ;  Klinika hepatogastroenterologie IKEM, Praha
Published in: Prakt. Lék. 2023; 103(1): 3-9
Category: Various Specialization

Overview

Non-neoplastic portal vein thrombosis causes partial or complete occlusion of the portal vein or its branches with all the hemodynamic consequences. It is essential to distinguish between patients with portal vein thrombosis without preexisting liver disease arising from a prothrombotic state and/or local factor, and patients with portal vein thrombosis complicating liver cirrhosis. Earlier diagnosis by more acceccible imaging modalities, and thus earlier initiation of effective anticoagulation, significantly improved the prognosis of noncirrhotic patients. Achieving recanalization of portal vein in patients with liver cirrhosis indicated for liver transplantation will enable or facilitate the transplantation itself.

Keywords:

portal vein thrombosis – portal hypertension – anticoagulation therapy – portal cholangiopathy – prothrombotic states


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