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Venetostart – The First Comprehensive Mobile Application with Practical Information for Venetoclax Treatment

27. 2. 2023

Abbvie has developed the comprehensive mobile application Venetostart with practical information needed in clinical practice for administering venetoclax (Venclyxto), which is indicated for the treatment of chronic lymphocytic leukemia (CLL) and acute myeloid leukemia (AML).

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What the Venetostart App can be used for

Upon opening the application, you can select the disease for which you are seeking information – CLL or AML:

In the CLL section, you will find information on venetoclax dosage in combination therapy in the 1st line, in combination therapy and monotherapy for relapsed/refractory disease, and on dosage adjustments for special patient groups and in case of drug interactions. Instructions on regimen adjustments that should be communicated to the patient are also provided. Based on tumor burden and creatinine clearance, it is possible to determine the risk of tumor lysis syndrome (TLS) in the app and find related prophylaxis and monitoring information. Another tab provides information on dosage adjustments in case of suspected TLS or other toxicity, allowing for the input of status developments and recommended further dosing.

In the AML section, there is information about dosing regimens in combination with hypomethylating agents, instructions on dosage adjustments for special patient groups, due to drug interactions, and guidance on informing patients about regimen adjustments. Here as well, you'll find the necessary information for assessing TLS risk, its prophylaxis, and guidelines for handling non-hematologic toxicity grades 3-4 and hematologic toxicity grade 4, with options for entering occurrence times, recurrences, and durations, including displaying the appropriate procedure.

Additionally, the app includes an illustrative video demonstrating the mechanism of action of venetoclax in both diseases (in English), a summary of product characteristics in Czech, references to venetoclax studies in the indicated uses, and explanations of frequently used abbreviations in the texts about venetoclax for CLL and AML.

How to Get the Venetostart App

The app is intended for healthcare professionals and can be downloaded for free to a mobile phone or tablet via QR code, or through the App Store or Google Play. The app is available for iOS and Android mobile operating systems. An access code is required.

Conclusion

The Venetostart mobile application offers healthcare professionals caring for patients with CLL and AML the possibility to always have practical information needed for the adequate and safe treatment of venetoclax at their fingertips. The app thus simplifies the use of this medication and consolidates necessary information into one place.

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