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Trazodone as a Multimodal and Multifunctional Antidepressant

17. 3. 2020 Source: Depression and Anxiety

Substances with multiple therapeutic effects, often depending on the dose, can be described as multifunctional. In low doses, trazodone has hypnotic effects, while its effective antidepressant action is evident at higher doses. This can be more frequently utilized now thanks to a modified-release formulation, which has the potential to improve the tolerability of antidepressant doses of trazodone.

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Prognostic Significance of Lymphopenia for Stratification of Patients with Follicular Lymphoma

The therapy of follicular lymphoma (FL) is guided by several prognostic indices, such as the…
17. 3. 2020 Source: Non-Hodgkin Lymphomas and CLL
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Benefit of Maintenance Therapy with Olaparib in Newly Diagnosed Advanced Ovarian Cancer

The SOLO-1 study evaluated whether the use of the PARP inhibitor olaparib in the maintenance…
17. 3. 2020 Source: Ovarian and Breast Cancer

Metamizole in perioperative treatment in children under 14 years – results of a questionnaire survey from practice

A recent survey among German-speaking physicians evaluated the use of non-opioid analgesics in…
17. 3. 2020 Source: Analgesia
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Spiolto Respimat System – Innovation for Easier Inhalation

Inhalation delivery is the most preferred method of drug administration in chronic obstructive…
16. 3. 2020 Source: COPD

Prognostic Significance of Subclinical Joint Changes on MRI in Hemophilia

Experience shows that monitoring joint changes, especially subclinical ones, is very necessary in…
16. 3. 2020 Source: Hemophilia

Safety and Tolerance of Metamizole in Postoperative Analgesia in Children

Due to the potential serious side effects of metamizole, the use of this drug in children is often…
16. 3. 2020 Source: Analgesia
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Type of Pharmacological Thromboprophylaxis and Disease Stage as Risk Factors for Bleeding in Patients After Colorectal Cancer Surgery

Japanese authors of a study published last year in the World Journal of Surgical Oncology attempted…
14. 3. 2020 Source: Thromboprophylaxis
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European Survey on Prophylactic Treatment of Chemotherapy-Induced Nausea and Vomiting Suggests Gaps in Practice and Ways to Improve

Using recommended guidelines for antiemetic prophylaxis can prevent chemotherapy-induced nausea and…
13. 3. 2020 Source: Antiemetic Therapy

New drugs in CLL may also carry specific risks of adverse effects. How to minimize and manage them?

The possibilities for the treatment of chronic lymphocytic leukemia (CLL) have greatly expanded in…
13. 3. 2020 Source: Chronic Lymphocytic Leukemia
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