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Pharmacokinetics and Safety of Bilastine 10 mg in Children Aged 6–11 Years
The second-generation antihistamine bilastine is approved in Europe for the treatment of allergic rhinoconjunctivitis and urticaria from the age of 6 years. Recently, results from two post hoc analyses on the pharmacokinetics and safety of bilastine in children aged 6–11 years have been published.

Safety and Tolerability of Bilastine in the Treatment of Chronic Urticaria in Children
Chronic urticaria is less common in pediatric patients compared to the acute form, but it always…

Transition of Hemophilia A Patients with a History of Coagulation Factor Inhibitor to Emicizumab
During the World Federation of Hemophilia (WFH) conference, held virtually in June 2020,…

DPP-4 Inhibitors May Prevent SARS-CoV-2 Entry into Cells
Since the new type of coronavirus SARS-CoV-2 utilizes the DPP-4 receptor to enter human cells,…

An Introductory Word to the Section on Hereditary Angioedema — MUDr. Roman Hakl, Ph.D.
Hereditary angioedema (HAE) is a genetically conditioned disease, currently classified into HAE…

Algorithm for Choosing Antidiabetics in Patients with Type 2 Diabetes
As of June 1, 2020, general practitioners can prescribe antidiabetics from the group of so-called…

Major Orthopedic Procedures in Patients with Inhibitor Treated with Emicizumab
Italian authors presented the results of a study of a small series of hemophilia patients with…

Comorbidities of Migraine and Their Impact on Pain Frequency and Intensity
The MAST study, published in March of this year in the prestigious The Journal of Headache and…

What is the significance of hormones in the pathophysiology of migraine?
Migraine is a complex neurovascular disease characterized by the dysfunction of the nociceptive…

When to Initiate Dabigatran Therapy in Patients with Atrial Fibrillation After First Ischemic Stroke?
After a cardioembolic ischemic stroke (iCMP), approximately 5% of patients experience a recurrence…
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