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Observational Study of Pegylated rVIII Administration in Real Clinical Practice

21. 9. 2020 Source: Hemophilia

A recently published article by American hematologists provided valuable information about the treatment with pegylated recombinant factor VIII (rVIII) in real clinical practice. This is the most extensive observational study to date that evaluates the clinical effect of the treatment and at the same time compares the consumption of FVIII in people with hemophilia A who have changed medication from normal half-life (SHL) or extended half-life (EHL) concentrates to pegylated rVIII.

Cost-effectiveness in Bleeding Control for Acquired Hemophilia A

A pharmacoeconomic analysis showed favorable cost-effectiveness of activated prothrombin complex…
18. 9. 2020 Source: Hemophilia
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Comparison of Efficacy of Bisoprolol and Metoprolol ZOK in Patients with Mild to Moderate Hypertension – Results of the CREATIVE Study

Suppression of increased activity in the sympathoadrenal system is currently one of the main goals…
17. 9. 2020 Source: Cardiovascular Continuum
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Impact of Adequate Protein Intake on Morbidity and Mortality in Critically Ill Patients

The following text provides a summary of findings from clinical studies in the field of nutritional…
16. 9. 2020 Source: Parenteral Nutrition
Srdeční komora

How to Achieve Left Ventricular Reverse Remodeling and Improve Outcomes in Heart Failure? Summary from HFA ESC Webinar

The current treatment algorithm for chronic heart failure with reduced ejection fraction (HFrEF) is…
16. 9. 2020 Source: Chronic Heart Failure and Lipidology
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The Importance of Adequate Protein Intake in Critical Patients – Analysis of Data from an International Study

Adequate protein intake is a necessary part of care for critically ill patients and mitigates…
16. 9. 2020 Source: Parenteral Nutrition
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Direct Comparison of the Efficacy and Safety of Anti-EGFR Antibodies in the Combined Therapy of Chemotherapy-Refractory Metastatic Colorectal Cancer

The combination of anti-EGFR therapy with irinotecan has brought benefits to patients with…
15. 9. 2020 Source: Colorectal Cancer

Glucagon for Intranasal Application Newly Available Also in the Czech Republic

Intramuscular administration of glucagon was until recently the only option for acute treatment of…
15. 9. 2020 Source: Modern Treatment of Diabetes
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Use of Tiapride in the Treatment of Behavioral Disorders in Geriatric Patients

Hand in hand with the increasing number of people reaching an older age, there is also a rise in…
15. 9. 2020 Source: Geriatric Patient
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Trifluridine/tipiracil, regorafenib, or supportive therapy? Factors affecting the success of mCRC treatment

Currently, there are no biomarkers available to help decide, for a specific patient with refractory…
15. 9. 2020 Source: Treatment of Gastrointestinal Carcinomas
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