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Tumor markes in renal cancer: help for diagnosis, prognosis, treatment and follow up


Authors: V. Vít
Authors‘ workplace: Urologická klinika FN Brno
Published in: Urol List 2010; 8(2): 11-15

Overview

The author of this review deals with the issue of localized renal carcinoma in patients undergoing surgical treatment. He outlines some of the prognostic factors – standard clinical and patological features used in clinical practice (symptomatology, TNM clasification, histopatological grade, microvascular invasion) and also some new molecular biological markers currently under investigation (HIF-1α, VEGF, Ki67, p53, CXCR 3, MMP 2, MMP 9, IMP 3). He also deals with the role of DNA microchip technologies in renal tumours research.

Key words:
renal carcinoma, prognostic factors, molecular biological markers, DNA microchip technologies


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