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Mucormycosis – review of literature and case report


Authors: M. Čerňan 1;  T. Szotkowski 1;  R. Machová 1;  M. Palová 1;  P. Hamal 2;  E. Faber 1
Authors‘ workplace: Hemato-onkologická klinika LF UP a FN Olomouc 1;  Ústav mikrobio logie LF UP a FN Olomouc 2
Published in: Transfuze Hematol. dnes,27, 2021, No. 2, p. 137-145.
Category: Review/Educational Papers
doi: https://doi.org/10.48095/cctahd2021137

Overview

Mucormycosis represents a heterogenous group of rare invasive fungal infections associated with an aggressive course and high mortality. In Europe, patients undergoing intensive treatment for haematological malignancies and allogeneic hematopoietic stem cell transplantation are at the highest risk of mucormycosis infection. The lungs are the most frequently affected site in these patients. This work summarizes current data regarding epidemiology, dia­gnosis and treatment recommendations. The review article is followed by a case report regarding the rare manifestation of cutaneous mucormycosis in an acute myeloid leukaemia patient. The aim of this work is to provide current information regarding this group of opportunistic infections with an increasing clinical impact. Only early dia­gnosis and rapid initiation of complex therapy can lead to a favourable outcome and complete cure.

Keywords:

invasive fungal infection – mucormycosis – acute myeloid leukaemia – antimycotics


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Labels
Haematology Internal medicine Clinical oncology

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Transfusion and Haematology Today

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