Skin and soft tissue infections (SSTIs)

Czech version

Authors: R. Gürlich ¹; V. Adámková ²; J. Ulrych ³; H. Brodská ⁴; V. Janík ⁵; J. Lindner ⁶; E. Havel ⁷
Authors‘ workplace: Chirurgická klinika FNKV a 3. LF Univerzity Karlovy přednosta: prof. MUDr. R. Gürlich, CSc. ¹; Klinická mikrobiologie a ATB centrum VFN Praha a 1. LF Univerzity Karlovy primář: MUDr. V. Adámková ²; I. chirurgická klinika VFN a 1. LF Univerzity Karlovy přednosta: prof. MUDr. Z. Krška, CSc. ³; Ústav lékařské biochemie a laboratorní diagnostiky přednosta: prof. MUDr. T. Zima, DrSc. ⁴; Radiodiagnostická klinika FNKV a 3. LF Univerzity Karlovy zastupující přednosta: MUDr. L. Večeřová ⁵; II. chirurgická klinika kardiovaskulární chirurgie VFN v Praze a 1. LF Univerzity Karlovy přednosta: prof. MUDr. J. Lindner, CSc. ⁶; Chirurgická klinika FNHK a LF HK přednosta: MUDr. M. Leško, Ph. D ⁷
Published in: Rozhl. Chir., 2016, roč. 95, č. 4, s. 141-146.
Category: Review

Overview

Skin and Soft Tissue Infections (SSTIs) encompass a wide spectrum of inflammatory diseases of the skin, subcutis, fascia and muscles. Recent national trends indicate increasing rates of patients treated for these diagnoses at outpatient surgical department, but also of patients hospitalized with severe forms of SSTIs. Up to 90% fatality rates are reported in the literature for the most severe forms, resulting from underestimation of initial symptoms and therefore delayed onset of radical therapy only the phase of septic shock. The paper provides an interdisciplinary review of essential principles of the diagnosis and therapy of SSTIs, reflecting present knowledge supported by evidence-based medicine.

Key words:
skin and soft tissue infections – SSTIs – necrotizing fasciitis – diagnosis – therapy

Sources

1. Center for Drug Evaluation and Research (CDER). Uncomplicated and complicated skin and skin-structure infections – developing antimicrobial drugs for treatment. 1998. www.fda.gov/ cder/guidance/2566dft.pdf.

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Article was published in

Perspectives in Surgery

2016 Issue 4