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Anaplastic carcinoma of the thyroid gland


Authors: P. Bavor 1;  J. Neumann 1;  S. Smutný 2;  P. Vlček 3
Authors‘ workplace: Chirurgická klinika 2. LF UK a FN Motol 1;  Chirurgické oddělení oblastní nemocnice Příbram 2;  Klinika nukleární medicíny a endokrinologie FN Motol 3
Published in: Rozhl. Chir., 2012, roč. 91, č. 10, s. 550-553.
Category: Original articles

Článek byl věnován prof. MUDr. Jiřímu Hochovi, CSc. při příležitosti jeho významného životního jubilea.
Článek je vypracován s podporou grantu: IGA MZČR, NT 11455-5/2010

Overview

Introduction:
The characteristics of anaplastic carcinoma, its biological properties, incidence and possibilities of therapeutic influence are described in the article.

Material and methods:
The authors present a cohort of patients with anaplastic carcinoma of the thyroid gland (ATC) who were operated on at the Department of Surgery during the last 5 years.

Results:
The destiny of all the patients with histologically confirmed anaplastic carcinoma is followed, the survival period is evaluated. With regard to the small patient cohort there was no further statistical processing.

Conclusion:
The role of the surgeon in the treatment of anaplastic carcinoma as well as the necessity of the multimodal way of treatment is evaluated.

Key words:
anaplastic carcinoma of the thyroid gland – biological treatment – median of survival


Sources

1. Siironen P, Hagström J, Maenpaa HO, Louhimo J et al. Anaplastic and poorly differentiated thyroid carcinoma: Therapeutic strategies and treatment outcome of 52 consecutive patiens. Oncology 2010;79:400–408.

2. Perri F, Di Lorenzo G, Scarpati GDV, Buonerba C. Anaplastic thyroid carcinoma: A comprehensive review of current and future therapeutic options. World J Clin Oncol 2011;3:150–157.

3. Sugitani I, Miyauchi A, Sugino K, Okamoto T, Yoshida A, Suzuki S. Prognostic factors and treatment outcomes for anaplastic thyroid carcinoma: ATC research consortium of Japan cohort study of 677 patients. World J. Surgery 2012;2:268–276.

4. Vlček P, Neumann J. Karcinom štítné žlázy – pooperační sledování nemocných. Maxdorf - Jessenius 2002:11, 29, 31, 40, 125, 178.

5. Dvořák J, Neumann J. Chirurgická léčba karcinomu štítné žlázy. Cas Lek Cesk 1995;12:374–377.

6. Vlasák V. Příspěvek k diagnostice a chirurgickému léčení anaplastického karcinomu štítné žlázy. Rozhl Chir 1985;3:180–185.

7. Němec J, Chytrý P, Dvořák J, Vlcek P, Neradilová M, Racek P. The effect of gender on prevalence and survival in thyroid carcinoma. Vnitr Lek 1996;9:602–604.

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