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Phytotherapy of skin wounds – overview of experimental and clinical studies in the first decennium of the 21st century


Authors: Ivan Kováč 1;  Peter Gál 2,3;  Ján Mojžiš 4
Authors‘ workplace: Univerzita Pavla Jozefa Šafárika v Košiciach, Lekárska fakulta, II. chirurgická klinika, Slovenská republika 1;  Východoslovenský ústav srdcových a cievnych chorôb, a. s., Úsek pre biomedicínsky výskum, Košice, Slovenská republika 2;  Univerzita Karlova v Praze, 1. lékařská fakulta, Ústav histologie a embryologie, Česká republika 3;  Univerzita Pavla Jozefa Šafárika v Košiciach, Lekárska fakulta, Ústav farmakológie, Slovenská republika 4
Published in: Čas. Lék. čes. 2012; 151: 423-427
Category: Review Articles

Overview

Delayed wound healing presents a significant burden for the patient and healthcare system. One of many possibilities how to improve the process of wound healing and to prevent development of unwanted complications is the use of herbal substances which are still commonly used in folk medicine. This review gives an overview of experimental and clinical studies related to phytotherapeutic approaches of skin wound healing which have during the 21st century been indexed by the largest biomedical database NCBI – PubMed.

Key words:
phytotherapy, skin wound healing, plant extracts.


Sources

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20. Nayak BS, et al. Catharanthus roseus flower extract has wound–healing activity in Sprague Dawley rats. BMC Complement Altern Med 2006; 21: 6–41.

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22. Paocharoen V, et al. The efficacy and side effects of oral Centella asiatica extract for wound healing promotion in diabetic wound patients. J Med Assoc Thai 2010; 93: 166–170.

23. Priya KS, et al. Healing potential of Datura alba on burn wounds in albino rats. J Ethnopharmacol 2002; 83: 193–199.

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27. Shivhare Y, et al. Wound healing potential of methanolic extract of Trichosanthes dioica Roxb (fruits) in rats. J Ethnopharmacol 2010; 127: 614–619.

28. Teoh SL, et al. The effect of topical extract of Momordica charantia (bitter gourd) on wound healing in nondiabetic rats and in rats with diabetes induced by streptozocin. Clin Exp Dermatol 2009; 34: 815–822.

29. Zippel J, et al. Arabinogalactans from Mimosa tenuiflora (Willd.) Poiret bark as active principles for wound–healing properties: Specific enhancement of dermal fibroblast activity and minor influence on HaCaT keratinocytes. J Ethnopharmacol 2009; 124: 391–396.

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