Regulatory Network of Transcription Factors: Their Key Role in the Development and Function of Pancreas
Authors:
P. Lukášová; J. Včelák; M. Vaňková; D. Vejražková; B. Bendlová
Authors‘ workplace:
Endokrinologický ústav, Praha
Published in:
Čas. Lék. čes. 2007; 146: 227-234
Category:
Review Article
Overview
Recent molecular biological studies of the pancreatic development have shed new light on the cause of MODY and diabetes mellitus type 2. The identification of transcription factors participating in the regulatory networks cooperating in the development and in adult exocrine and endocrine pancreas enabled the better understanding of the genetic background and subsequent phenotypic features of diabetes.
Key words:
transcription factor, pancreas, mutation, polymorphism, MODY, diabetes mellitus type 2, insulin.
Labels
Addictology Allergology and clinical immunology Angiology Audiology Clinical biochemistry Dermatology & STDs Paediatric gastroenterology Paediatric surgery Paediatric cardiology Paediatric neurology Paediatric ENT Paediatric psychiatry Paediatric rheumatology Diabetology Pharmacy Vascular surgery Pain management Dental HygienistArticle was published in
Journal of Czech Physicians
Most read in this issue
- Neurosteroids and Their Function
- Relationships Between the „Eating Inventory“ Factors, Socioeconomic Status, Anthropometric Body Adiposity Indexes and Health Risks in Czech Population
- Obesity Based on Mutation of Genes Involved in Energy Balance
- Growth Hormone Treatment in the Institute of Endocrinology