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Ischemia-Modified Albumin: New Marker of Myocardial Ischemia?


Authors: J. Dušek;  M. Tichý 1;  J. Šťásek;  J. Bis;  J. Gregor 2;  R. Pudil;  J. Vojáček
Authors‘ workplace: I. interní klinika FN, Hradec Králové ;  Ústav klinické biochemie a diagnostiky FN, Hradec Králové 1;  Plicní klinika FN, Hradec Králové 2
Published in: Čas. Lék. čes. 2005; 144: 295-297
Category: Review Article

Overview

The Albumin Cobalt Binding Test is a quantitative in vitro diagnostic test used on human serum that detects Ischemia-Modified Albumin by measuring the cobalt binding capacity of albumin in human serum. Ischemia modified albumin is intended for use in conjunction with ECG and cardiac troponin as an aid to short term risk stratification of patients presenting with chest pain suggestive of cardiac origin. Thus, in patients with chest pain or equivalent symptoms suggestive of cardiac origin, with non-diagnostic ECG and normal troponin, a negative IMA can be used as an aid to rule out acute coronary syndrome (ACS) in low risk patients. 

Key words:
ischemia modified albumin, myocardial ischemia.


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