Urinary Tract Infections - All the Time Topical Problem

Overview

By analyzing the standard works in the scientific world literature, it was possible to construct a contemporaryview on the etiology and antibiotic therapy of some urinary tract infections. It can be stated, that the most effectiveremedies are cotrimoxazol and fluoroquinolones. In contrary to beta-lactam antibiotics, cotrimoxazole and fluoro-quinolones work with a rapid bactericidal effect, they have long elimination half-times and better sterilizationcapacity in the periurethral region, and it use brings minimal risk of recurrence of the infection. This facts arecompared with results of bacteriological investigation of urine, which were done in the microbiological laboratoriesof University Hospital Hradec Králové, Czech Republic, in 1998. The most frequent origins of urinary tract infectionsare Escherichia coli and Enterococcus spp. Stains. The are keeping high susceptibility to contrimoxazole, furantoinand oxoline acid. The other Gram negative rods isolated from hospitalised patients are highly resistant to most ofantimicrobial agents included fluorochinolons, which resistance culminates to 50 %. The widest spectrum ofpathogens and the highest resistance was found in the hospitalised patients of the university hospital. High percentagesof resistant strains was also in patients from the district hospitals. The results are discussed.

Key words:
urinary tract infections, cultivation.