DRESS syndrome

Czech version

Authors: Monika Adamcová; Igor Šturdík; Tomáš Koller; Juraj Payer
Authors‘ workplace: V. interná klinika LF UK a UN Bratislava, Nemocnica Ružinov, Slovenská republika
Published in: Vnitř Lék 2016; 62(4): 334-337
Category: Case Reports

Overview

DRESS syndrome (Drug Rash with Eosinophilia and Systemic Symptoms) is severe drug-induced allergic-type reaction which occurs few days to weeks after taking a drug in a predisposed patient. Organ damage, eosinophilia and skin rash are typical at presentation. Corticotherapy is often necessary in severe cases. In this report we describe a case of 56-year old female with fever, elevated liver tests and skin rash. DRESS syndrome was diagnosed and allopurinol was indentified as a causative drug. Due to possible fatal outcome, DRESS syndrome should be considered in a differential diagnosis of all patients presenting with similar signs and symptoms.

Key words:
allopurinol – DRESS syndrome – hepatopathy

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