Prokinetic agents – their contribution to practice of gastroenterology

Czech version

Authors: A. Hep ¹; Jiří Dolina ²
Authors‘ workplace: Interní gastroenterologická klinika Lékařské fakulty MU a FN Brno, pracoviště Bohunice, přednosta prof. MUDr. Aleš Hep, CSc. ¹; Endoskopické centrum FN Brno, pracoviště Bohunice, přednosta prim. MUDr. Jiří Dolina, Ph. D. ²
Published in: Vnitř Lék 2011; 57(9): 693-696
Category: 65th birthday Mudr. Jany Laciné and and 60th birthday Milana Tržila

Overview

Motility plays a fundamental role in the functioning of the gastrointestinal tract. Prokinetic agents are thus an important treatment modality in patients with functional and certain organ diseases with underlying functional modifications. Gastro-oesophageal reflux disease is frequently associated with a disorder of oesophageal motility, an alteration of gastric evacuation may manifest as an atypical dyspeptic complaint. Prokinetic agents may also be effective in other disease states, such as diabetic gastroparesis, malignant conditions associated with nausea and vomiting, motility disorders in preterm babies etc.

Key words:
functional disorders – prokinetic agents – gastro-oesophageal reflux disease – irritable bowel syndrome – dyspeptic syndrome – motility

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