Current perspective of treating hypertension in pregnancy
Authors:
M. Koucký
Authors‘ workplace:
Gynekologicko-porodnická klinika 1. lékařské fakulty UK a VFN Praha, přednosta prof. MUDr. Alois Martan, DrSc.
Published in:
Vnitř Lék 2011; 57(9): 728-31
Category:
65th birthday Mudr. Jany Laciné and and 60th birthday Milana Tržila
Overview
The author deals with the contemporary perspective on treatment hypertension in pregnancy. The article highlighted that hypertension treatment should be conducted not only with regard to the mother, but also to the possible negative impact on supply to the fetus. New information, particularly in the pathophysiology of pregnancy related hypertension show that in these diagnoses is vasoconstriction in placental microcirculation quite common. Inadequate treatment may have adverse effects on uteroplacental flow with potential risks to the fetus. The treatment of choice in pregnancy relatedy hypertension are methyldopa, calcium antagonists and labetalol.
Key words:
pregnancy – hypertension – preeclampsia – methyldopa
Sources
1. Gifford R, August P, Cunningham G et al. The National High Blood Pressure Education Program Working Group on High Blood Pressure in Pregnancy, Bethesda, National Institutes of Health and National Heart, Lung, and Blood Institute 2000.
2. Zhang J, Klebanoff MA, Roberts JM. Prediction of adverse outcomes by common definitions of hypertension in pregnancy. Obstet Gynecol 2001; 97: 261–267.
3. ACOG Committee on Practice Bulletins – Obstetrics. ACOG Committee on Practice Bulletins – Obstetrics. Diagnosis and management of preeclampsia and eclampsia. Number 33, January 2002. Obstet Gynecol 2002; 99: 159–167.
4. Egerman RS, Sibai BM. HELLP syndrome. Clin Obstet Gynecol 1999; 42: 381–389.
5. Měchurová A, Andělová K. Hypertenze v graviditě – doporučený postup. Česká gynekol 2010; 75 (Suppl 1): 20–25.
6. Abalos E, Duley L, Steyn DW et al. Antihypertensive drug therapy for mild to moderate hypertension during pregnancy. Cochrane Database Syst Rev 2007; 1: CD002252.
7. Creasy K, Resnik R, Iams JD et al. Creasy and Resnik’s Maternal-Fetal Medicine: Principles and Practice. 6th ed. Philadelphia, PA: Saunders Elsevier 2009.
Labels
Diabetology Endocrinology Internal medicineArticle was published in
Internal Medicine
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