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Primary hepatic carcinoid


Authors: J. Plášek 1;  M. Vybíralová 2;  J. Dvořáčková 3;  A. Petrušková 4;  J. Sagan 5;  M. Golián 6;  V. Hrabovský 1;  N. Petejová 1;  Arnošt Martínek 1
Authors‘ workplace: Interní klinika Lékařské fakulty Ostravské Univerzity a FN Ostrava, přednosta doc. MUDr. Arnošt Martínek, CSc. 1;  Onkologická klinika Lékařské fakulty Ostravské Univerzity a FN Ostrava, přednosta prim. MUDr. David Feltl, Ph. D., MBA 2;  Ústav patologie Lékařské fakulty Ostravské Univerzity a FN Ostrava, přednostka prim. MUDr. Jana Dvořáčková, Ph. D. 3;  Klinika nukleární medicíny Lékařské fakulty Ostravské Univerzity a FN Ostrava, přednosta prim. MUDr. Otakar Kraft, Ph. D., MBA 4;  Klinika infekčního lékařství Lékařské fakulty Ostravské Univerzity a FN Ostrava, přednosta prim. MUDr. Luděk Rožnovský, CSc. 5;  Radiodiagnostický ústav Lékařské fakulty Ostravské Univerzity a FN Ostrava, přednostka prim. MUDr. Alena Jahodová 6
Published in: Vnitř Lék 2011; 57(6): 590-594
Category: Case Reports

Overview

Primary hepatic carcinoid (PHC) is considered to be particularly sporadic diagnosis; in current literature about 60 cases have been reported. Most of the patients present with abdominal pain, diarrhea, icterus, flush, weight loss or respiratory disease; even though the course of the disease might stay asymptomatic for a long time. An illuminating case of at presentation oligosymptomatic 65-year-old patient, which was after extensive examination based on Octreoscan and histological verification diagnosed to have PHC, is reported. Paliative therapy with somatostatine analogues followed. At autopsy 8 months later the clinical diagnosis of PHC was confirmed. PHC is difficult to diagnose both due to radiological similarity to other hepatic lesions and demanding exclusion of other primary foci. The diagnosis of PHC is based on negative imaging techniques result in other possible localizations. Minimal symptomatology in stage of generalization, atypical primary localization and rapid progression is of interest in current case.

Key words:
carcinoid – octreoscan – 5-HIAA – Sandostatin LAR


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Diabetology Endocrinology Internal medicine
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