#PAGE_PARAMS# #ADS_HEAD_SCRIPTS# #MICRODATA#

Transplantation of haematopoietic cells


Authors: M. Krejčí;  J. Mayer;  Z. Adam;  J. Vorlíček
Authors‘ workplace: Interní hematoonkologická klinika Lékařské fakulty MU a FN Brno, pracoviště Bohunice, přednosta prof. MUDr. Jiří Vorlíček, CSc.
Published in: Vnitř Lék 2009; 55(9): 738-745
Category: 80th Birthday - prof. MUDr. Miloš Štejfa, DrSc., FESC

Overview

Autologous and allogeneic transplantations of haematopoietic cells form an important part of treatment of, particularly haematological, malignancies but have their place in the treatment of other diseases as well. Transplantation brings permanent remission in a number of patients. However, transplantation, and the allogeneic one in particular, is associated with a range of complications. The following review paper provides information on the types of transplants, their collection and processing, on the options for and ways to seek suitable donors of haematopoietic cells. Other sections of the paper focus on preparatory pre-transplantation regimens and complications that might occur after the transplantation. Finally, the paper reviews clinical uses of haematopoietic cell transplantations and provides a summary of diagnoses in which this treatment method can be applied.

Key words:
autologous transplantation – allogeneic transplantation – haematopoietic cells


Sources

1. Basara N, Kiehl MG, Fauser AA. New therapeutic modalities in the treatment of graft-versus-host disease. Crit Rew Oncol Hematol 2001; 38: 129–138.

2. Faber E. Transplantace krvetvorných buněk. In: Indrák K et al (eds). Hematologie. Praha: Triton 2006: 237–247.

3. Filipovich AH, Weisdorf D, Pavletic S et al. National institute of health consensus development project on criteria for clinical trials in chronic graft-versus-host disease: I. Diagnosis and staging working group report. Biol Blood Marrow Transplant 2005; 11: 945–956.

4. Grathwohl A, Baldomero H, Fauendorfer K et al. Results of the EBMT activity survey 2005 on haematopoietic stem cell transplantation: focus on increasing use of unrelated donors. Bone Marrow Transplant 2007; 39: 71–87.

5. Ljungman P, Urbano-Ispizua A, Cavazzana-Calvo M et al. Allogeneic and autologous transplantation for haematological diseases, solid tumours and immune disorders: definitions and current practice in Europe. Bone Marrow Transplant 2006; 37: 439–449.

6. Mayer J, Cetkovský P, Krejčí M. Ste­roid-rezistentní akutní reakce štěpu proti hostiteli. Transfuze Hematol dnes 2007; 13: 192–199.

7. Mayer J, Starý J. Vysokodávkovaná chemoterapie a transplantace krvetvorných buněk. In: Mayer J et al (eds). Leukemie. Praha: Grada Publishing 2002: 196–212.

8. Mayer J. Co jsou nemyeloablativní transplantace krvetvorných buněk? Vnitř Lék 2001; 47 (Suppl 1): 29–33.

9. Przepiorka D, Weisdorf D, Martin P et al. Consensus conference on acute GVHD grading. Bone Marow Transplant 1995; 15: 825–828.

10. Sullivan KM. Graft versus host disease. In: Thomas ED, Blume KG, Forman SJ et al (eds). Hematopoietic Cell Transplantation. Oxford: Blackwell Science 1999: 515–536.

11. Vaňásek J, Starý J, Kavan P et al. Transplantace kostní dřeně. Praha: Galén 1996.

Labels
Diabetology Endocrinology Internal medicine

Article was published in

Internal Medicine

Issue 9

2009 Issue 9

Most read in this issue
Topics Journals
Login
Forgotten password

Enter the email address that you registered with. We will send you instructions on how to set a new password.

Login

Don‘t have an account?  Create new account

#ADS_BOTTOM_SCRIPTS#