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Proton radiotherapy – dosimetric advantages for patients with breast cancer


Authors: A. Pásztorová;  A. Haas;  S. Al-Hamami;  J. Abrahámová;  J. Kubeš;  B. Ondrová;  M. Andrlík;  D. Šimánková
Authors‘ workplace: Proton Therapy Center Czech, s. r. o., Praha Primář: doc. MUDr. Jiří Kubeš, PhD.
Published in: Prakt. Lék. 2024; 104(2): 84-92
Category: Of different specialties

Overview

Adjuvant radiotherapy is a frequently used treatment option for non-metastatic breast cancer. Although highly effective, it can be burdened with several negative side-effects that may increase the risk of cardiovascular and pulmonary diseases, secondary malignancies, and according to recent data, may lead to unwanted suppression of the immune system.

Proton radiotherapy has unique dosimetric advantages that offer the possibility of reducing the integral dose and unwanted dose to the surrounding organs at risk, while simultaneously allowing for optimal coverage of the treatment volume. This benefit becomes more evident in larger or more complex target volumes.

Treatment plans with increased complexity, such as those for bilateral breast cancer, complicated or arched chest shapes (e.g., pectus excavatum), or those involving irradiation of the internal mammary nodes, stand to benefit significantly from proton therapy.

In this article, we highlight situations in which proton radiotherapy offers pronounced dosimetric advantages for breast cancer patients.

Keywords:

breast cancer – proton radiotherapy – dosimetric advantages


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adresa pro korespondenci:
MUDr. Andrea Pásztorová
Proton Therapy Center Czech, s. r. o.
Budínova 2437/1a, 180 00 Praha 8
email:
andrea.pasztorova@ptc.cz

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