Detekce toluenu, metanolu a kyseliny mravenčí při pitvě pacienta závislého na rozpouštědlech

English version Czech version

: Kinoshita Hiroshi ¹; Tanaka Naoko ¹; Takakura Ayaka ¹; Kumihashi Mitsuru ¹; Jamal Mostofa ¹; Ito Asuka ¹; Tsutsui Kunihiko ²; Kimura Shoji ¹; Matsubara Shuji ³; Ameno Kiyoshi ¹
: Department of Forensic Medicine, Faculty of Medicine, Kagawa University, Kagawa Japan ¹; Health Sciences, Faculty of Medicine, Kagawa University, Kagawa, Japan ²; Community Health Care Education Support Center and Postgraduate Clinical Education Center, Kagawa University Hospital, Kagawa, Japan ³
: Soud Lék., 64, 2019, No. 2, p. 20-22
: Original Article

V tomto článku je prezentován smrtelný případ zneužití rozpouštědla. Čtyřicetiletý muž byl nalezen mrtvý ve svém domě s mnoha prázdnými vinylovými sáčky a lahvemi obsahujícími směs toluenu a metanolu v okolí. Pitva neprokázala žádné známky vnějšího poranění a vyloučila i fyzická onemocnění. Následné šetření odhalilo, že oběť dlouhodobě zneužívala toluen. V krvi ze stehenní žíly byla zjištěna koncentrace toluenu 20,1 mg/l, metanolu 210 mg/l a kyseliny mravenčí 25,2 mg/l. Nebyl detekován žádný etanol a screening léků pomocí TriageTM (Biosite Diagnostic, San Diego, CA) byl rovněž negativní. Koncentrace toluenu ve femorální krvi byla na letální úrovni a koncentrace metanolu byla v toxickém rozmezí. Těžká, relativně dlouhodobá expozice toluenu vyplývala z vysoké koncentrace kyseliny hippurové v moči (12,91 g/l). Z pitevních nálezů, výsledků toxikologického vyšetření a vyšetřování ze strany úřadů vyplývalo, že příčina smrti byla otrava toluenem a metanolem.

Klíčová slova:

rozpouštědlo – methanol – toluen – kyselina mravenčí – abusus – fatální intoxikace

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Anatomical pathology Forensic medical examiner Toxicology

Sexual homicide attempt: A case report and a short review of the literature

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Forensic Medicine

2019 Issue 2