An Autopsy Case of Carbamazepine Poisoning
Authors:
Hiroshi Kinoshita *; Kimiko Morikawa **; Azumi Kuze ***; Yasushi Nagasaki **; Motonori Takahashi ****; Minori Nishiguchi ****; Hajime Nishio ****; Yasuhiro Ueno ***; Mostofa Jamal *; Yusuke Kubo *; Naoko Tanaka *; Kiyoshi Ameno *
Authors‘ workplace:
Department of Forensic Medicine, Faculty of Medicine, Kagawa University, 1750-1, Miki, Kita, Kagawa, 761-0793, Japan
*; Hyogo Medical Examiners Office, Arata-cho 2-1-31, Hyogo-ku, Kobe, 652-0032, Japan
**; Division of Legal Medicine, Department of Environmental Health and Safety, Kobe University Graduate School of Medicine, 7-5-1, Kusunoki-cho, Chuo-ku, Kobe, 650-0017, Japan
***; Department of Legal Medicine, Hyogo College of Medicine, 1-1, Mukogawa-cho, Nishinomiya, Hyogo, 663-8501, Japan
****
Published in:
Soud Lék., 55, 2010, No. 2, p. 22-24
Overview
We present a case of fatal carbamazepine poisoning. Quantitative analysis of carbamazepine using high performance liquid chromatography, revealed that the concentrations of carbamazepine were 50.2 μg/ml in the femoral venous blood and 60.3 μg/ml in the heart blood, respectively, and many unabsorbed tablets were also observed in the stomach contents. We concluded that the cause of death was due to carbamazepine overdose.
Key words:
carbamazepine – poisoning – high performance liquid chromatography
All correspondence concerning this paper should be addressed to:
Dr. H. Kinoshita,
Department of Forensic Medicine, Faculty of Medicine, Kagawa University,
1750-1, Miki, Kita, Kagawa, 761-0793, Japan
TEL: +81-87-891-2140
FAX: +81-87-891-2141
e-mail: kinochin@med.kagawa-u.ac.jp
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Labels
Anatomical pathology Forensic medical examiner ToxicologyArticle was published in
Forensic Medicine
2010 Issue 2
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