In-vivo interspecies transmission of carbapenemase KPC in a long-term treated female patient
Authors:
P. Polcarová 1; L. Hobzová 2; R. Kukla 3; P. Skořepa 4; J. Smetana 1; R. Šošovičková 1; R. Chlíbek 1
Authors‘ workplace:
Katedra epidemiologie, Fakulta vojenského zdravotnictví Univerzity obrany, Hradec Králové
1; Oddělení nemocniční hygieny, Fakultní nemocnice Hradec Králové
2; Ústav klinické mikrobiologie, Fakultní nemocnice Hradec Králové
3; III. interní gerontometabolická klinika, Fakultní nemocnice Hradec Králové
4
Published in:
Epidemiol. Mikrobiol. Imunol. 68, 2019, č. 2, s. 99-102
Category:
Short Communication
Overview
The increasing incidence of multiresistant bacterial strains is currently a serious health concern. These pathogens are often the cause of nosocomial infections with limited treatment options and high fatality rates. A case report is presented of an uncommon detection of four different species (Citrobacter freundii, Klebsiella pneumoniae, Escherichia coli, and Morganella morganii) producing the same type of carbapenemase, KPC-2, in a female patient during her complicated long-term hospital stay. Resistance was probably spread to other species by horizontal transmission of plasmids carrying the blaKPC-2 genes. The implementation of strict anti-epidemic measures prevented further spread of these carbapenem-resistant bacteria.
Keywords:
multiresistance – carbapenemase – KPC-2 – interspecies transmission – anti-epidemic measures
Sources
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Labels
Hygiene and epidemiology Medical virology Clinical microbiologyArticle was published in
Epidemiology, Microbiology, Immunology
2019 Issue 2
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