Hrabák J., Žemličková H., Bergerová T., Urbášková P.: Interpretation of the Susceptibility Test Results in Enterobacteria Producing 3^rd- and 4^th-Generation Cephalosporin- or Carbapenem-Hydrolyzing β-Lactamases

Czech version

Authors: J. Hrabák ¹; H. Žemličková ²; T. Bergerová ¹; P. Urbášková ²
Authors‘ workplace: Ústav mikrobiologie, Lékařská fakulta UK a Fakultní nemocnice v Plzni ¹; Národní referenční laboratoř pro antibiotika, Státní zdravotní ústav v Praze ²
Published in: Epidemiol. Mikrobiol. Imunol. 60, 2011, č. 1, s. 4-9

Overview

The interpretation of the susceptibility of Gram-negative rods to β-lactams is currently under discussion in CLSI and EUCAST – two authorities on determination of clinical breakpoints. This article summarizes the current knowledge about clinical breakpoints in enterobacteria and proposes guidance for clinical microbiology laboratories in the Czech Republic.

Keywords:
ESBL – AmpC – carbapenemases – KPC – MBL – interpretation – breakpoint.

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