Microsporidial Infection in Immunologicaly CompromisedHospitalized Patients

Overview

Microsporidia Encephalitozoon cuniculi, obligate intracellular spore – forming protozoan parasiteinfecting a wide range of vertebrate and invertebrate host, has been described as opportunisticpathogen in severely immunocompromised human host.An antibody immune response to the presence of antibodies against Encephalitozoon cuniculi wasinvestigated serologically using indirect immunofluorescence antibody test (IFAT). Of the totalnumber of 113 sera from immunologicaly compromised patients examined, 5 were positive at thetitre 1:32, 5 at the titre 1:64, and 6 at the titre 1:256. From total number of positive respondentpatients were 12 children and 4 adults.

Key words:
microsporidia – Encephalitozoon cuniculi – immunodeficient patients – IFAT.