#PAGE_PARAMS# #ADS_HEAD_SCRIPTS# #MICRODATA#

Warthin-like papillary carcinoma: Case report


Authors: Jana Jakešová;  Roman Boháč;  Jan Betlach
Authors‘ workplace: Oddělení patologie, Nemocnice Havlíčkův Brod
Published in: Čes.-slov. Patol., 59, 2023, No. 1, p. 23-25
Category: Original Articles

Overview

Warthin-like papillary thyroid carcinoma is a rare variant of papillary carcinoma with a very good prognosis. It is often associated with lymphocytic thyroiditis. Due to its typical histological picture resembling Warthin’s salivary gland tumor, the histological diagnosis is not difficult, usually does not require an accompanying immunohistochemical examination and is based on the presence of nuclear features typical of papillary carcinoma and the presence of oncocytes in a background of rich lymphocyte infiltrate. The preoperative cytologic examination is challenging, as many other lesions may have a similar picture. Women are more likely to get affected. It appears a decade earlier than the classic variant. Clinically, it presents similarly to a conventional papillary carcinoma. In our case report, we would like to present the case of a 56-year-old woman with non-toxic multinodular goiter, in whom the presence of this rare variant of papillary carcinoma was revealed by histological examination.

Keywords:

Thyroid – papillary carcinoma – Warthin-like papillary carcinoma – oncocytes


Sources

1. Wenig BM. Atlas of Head and Neck Pathology (2nd edn). Philadelphia: Elsevier; 2008: 910-938.

2. Goldblum JR, Lamps LW, McKenney JK, Myers JL. Rosai and Ackerman´s Surgical pathology (11th edn). Philadelphia: Elsevier; 2018: 297-308.

3. Wajahat M, Jeelani T, Gupta K, Bashir N. Warthin like papillary carcinoma – A rare variant of papillary carcinoma thyroid. Hum Pathol: Case Rep 2018; 13: 21-23.

4. Fletcher CD. Diagnostic histopathology of tumors (5th edn). Philadelphia: Elsevier; 2021: 1254-1261.

5. Yeo MK, Bae JS, Lee S, et al. The Warthin-Like Variant of Papillary Thyroid Carcinoma: A Comparison with Classic Type in the Patients with Coexisting Hashimoto´s Thyroiditis. Int J Endocrinol 2015; 2015: 456027.

6. Mishra A, Jayalakshmi V, Chaturvedi UP, Chikhale NP, Patel RD, Cherian S. Oncocytic variant of papillary thyroid carcinoma and associated Lymphocytic thyroiditis, a case report with review of literature. Int J Head Neck Surg 2013; 4(2): 89-91.

7. Paliogiannis P, Attene F, Trogu F, Trignano M. Warthin-Like Papillary Carcinoma of the Thyroid Gland: Case Report and Review of the Literature. Case Rep Oncol Med 2012; 2012: 689291.

8. Sahoo PK, Patnayak R, Khan PA, Jena A. Warthin-like variant of Papillary thyroid carcinoma – Case report of an uncommon tumour with review of literature. Int J Surg Case Rep 2020; 77: 9-11.

9. Olmos R, Munoz F, Donoso F, et al. Warthin- like and classic papillary thyroid cancer have similar clinical presentation and prognosis. Arch Endocrinol Metab 2021; 64(5): 542-547.

10. Kim J, Lim BJ, Hong SW, Pyo JY. Preoperative Cytologic Diagnosis of Warthin-like Variant of Papillary Thyroid Carcinoma. J Pathol Transl Med 2018; 52(2): 105-109.

11. Čáp J, Ryška A. Aspirační cytologie štítné žlázy (1.vydání). Hradec Králové: Nucleus HK; 2003: 74-81.

Labels
Anatomical pathology Forensic medical examiner Toxicology
Topics Journals
Login
Forgotten password

Enter the email address that you registered with. We will send you instructions on how to set a new password.

Login

Don‘t have an account?  Create new account

#ADS_BOTTOM_SCRIPTS#