Consensus recommendations from the Czech Head and Neck Cancer Cooperative Group (2019):
definition of surgical margins status, neck dissection reporting, and HPV/p16 status assessment
Authors:
Milan Vošmik 1; Jan Klozar 2; Jan Laco 3; Česká Kooperativní Skupina Pro Nádory Hlavy; Krku
Authors‘ workplace:
Klinika onkologie a radioterapie, Lékařská fakulta UK v Hradci Králové a Fakultní nemocnice Hradec Králové
1; Klinika otorinolaryngologie a chirurgie hlavy a krku, 1. lékařská fakulta UK v Praze a Fakultní nemocnice Motol
2; Fingerlandův ústav patologie, Lékařská fakulta UK v Hradci Králové a Fakultní nemocnice Hradec Králové
3
Published in:
Čes.-slov. Patol., 57, 2021, No. 1, p. 53-56
Category:
Reviews Article
Overview
The Czech Head and Neck Cancer Cooperative Group (CHNCCG) held a meeting in Tabor on 11-12 October 2019 with the aim of reaching an interdisciplinary consensus on some controversial points where international unity is absent. The meeting resulted in recommendations on resection margin size terminology (definition of terms: negative margin, close margin and positive margin) and on the adoption of terminology for neck dissections reporting according to the International Recommendation of the International Head and Neck Scientific Group and on assessment of HPV/p16 status in head and neck tumors.
Keywords:
head and neck cancer – recommendation – resection margin – neck dissection – HPV – p16
Sources
- Müller S, Boy SC, Day TA, et al. Data Set for the Reporting of Oral Cavity Carcinomas: Explanations and Recommendations of the Guidelines From the International Collaboration of Cancer Reporting. Arch Pathol Lab Med 2019; 143 (4): 439-446.
- The National Comprehensive Cancer Network (NCCN) for Head and Neck Cancers, Version 3.2019; URL: https://www.nccn.org/professionals/physician_gls/pdf/head-and-neck.pdf.
- Johnson RE, Sigman JD, Funk GF, et al. Quantification of surgical margin shrinkage in the oral cavity. Head Neck 1997; 19 (4): 281-286.
- Binahmed A, Nason RW, Abdoh AA. The clinical significance of the positive surgical margin in oral cancer. Oral Oncol 2007; 43 (8): 780-784.
- Gallo A, Manciocco V, Tropiano ML, et al. Prognostic value of resection margins in supracricoid laryngectomy. Laryngoscope 2004; 114 (4): 616-621.
- Mochiki M, Sugasawa M, Nibu K, et al. Prognostic factors for hypopharyngeal cancer: a univariate and multivariate study of 142 cases. Acta Otolaryngol Suppl 2007; 559: 136-144.
- Ansarin M, Santoro L, Cattaneo A, et al. Laser surgery for early glottic cancer: impact of margin status on local control and organ preservation. Arch Otolaryngol Head Neck Surg 2009; 135 (4): 385-390.
- Bernier J, Domenge C, Ozsahin M, et al. European Organization for Research and Treatment of Cancer Trial 22931: Postoperative irradiation with or without concomitant chemotherapy for locally advanced head and neck cancer. N Engl J Med 2004; 350 (19): 1945-1952.
- Cooper JS, Pajak TF, Forastiere AA, et al. Radiation Therapy Oncology Group 9501/Intergroup: Postoperative concurrent radiotherapy and chemotherapy for high-risk squamous-cell carcinoma of the head and neck. N Engl J Med 2004; 350 (19): 1937-1944.
- Bernier J, Cooper JS, Pajak TF, et al. Defining risk levels in locally advanced head and neck cancers: a comparative analysis of concurrent postoperative radiation plus chemotherapy trials of the EORTC (#22931) and RTOG (# 9501). Head Neck 2005; 27 (10): 843-850.
- Ferlito A, Robbins KT, Shah JP, et al. Proposal for a rational classification of neck dissections. Head Neck 2011; 33 (3): 445-450.
- Robbins KT, Clayman G, Levine PA, et al. Neck Dissection Classification Update: Revisions Proposed by the American Head and Neck Society and the American Academy of Otolaryngology - Head and Neck Surgery. Arch Otolaryngol Head Neck Surg 2002; 128 (7): 751–758.
- El-Naggar AG, Chan, JKC, Grandis JR, Takata T, Slootweg PJ (eds). WHO Classification of Head and Neck Tumours. Fourth edition. IARC WHO Classification of Tumours, No 9. Lyon, International Agency for Research on Cancer, 2017.
- Brierley JD, Gospodarowicz, MK, Witteking C (eds). UICC TNM klasifikace zhoubných novotvarů, 8. vydání 2017, česká verze 2017. Praha: Ústav zdravotnických informací a statistiky ČR; 2018.
- Laco J. Nádory hlavy a krku - Doporučený postup pro bioptické vyšetření, Společnost českých patologů 2018. URL: http://www.patologie.info/standardy/37.
Labels
Anatomical pathology Forensic medical examiner ToxicologyArticle was published in
Czecho-Slovak Pathology
2021 Issue 1
Most read in this issue
- A basic immunohistochemical panel for the diagnosis of soft tissue tumors
- Bone lesions – diagnostic approach using immunohistochemistry and molecular pathology
- An update on immunohistochemical and molecular genetic markers of selected soft tissue tumors
- Secondary pulmonary hypoplasia associated with calcified Meckel´s diverticulum with osseous metaplasia