Selected biomarkers in the primary tumors of the central nervous system: short review
Authors:
M. Švajdler ml. 1; B. Rychlý 2; L. Fröhlichová 1; P. Grossmann 3; A. Šteňo 4; F. Pataky 5
Authors‘ workplace:
Oddelenie patológie UNLP Košice, Trieda SNP1
1; Cytopathos, spol. s. r. o., Bratislava
2; Bioptická laboratoř, s. r. o., Plzeň
3; Neurochirurgická klinika, Nemocnica akad. L. Dérera, Bratislava
4; Neurochirurgická klinika UNLP, Košice
5
Published in:
Čes.-slov. Patol., 48, 2012, No. 2, p. 65-71
Category:
Review Articles – Neuropathology
Overview
Classification, grading and treatment of central nervous system tumors is currently based on morphology. Advances in molecular biology help to clarify pathogenesis, refine prognosis and detect potential targets for targeted therapy in a wide spectrum of CNS tumors. In this short review we present our view on selected diagnostic, prognostic and predictive biomarkers of primary CNS tumors, with an emphasis on application in daily praxis.
Keywords:
brain tumors – biomarkers – genetics – immunohistochemistry
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