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Post-fine-needle Aspiration Cytology Changes of Thyroid Gland


Authors: A. Ryška;  M. Ludví`ková;  L. Kholová;  J. Čáp 3
Authors‘ workplace: Fingerlandův ústav patologie, Lékařská fakulta UK a Fakultní nemocnice, Hradec Králové Šiklův patologicko-anatomický ústav, Fakultní nemocnice, Plzeň II. interní klinika, Lékařská fakulta UK a Fakultní nemocnice, Hradec Králové
Published in: Čes.-slov. Patol., , 2002, No. 2, p. 83-88
Category:

Overview

Due to the introduction of fine needle aspiration cytology (FNAC) to the routine clinical preoperative egamination surgical pathologists are faced with thyroid gland specimens with FNAC-induced secondary changes. These changes can cause diagnostic difficulties and be a Bource of incorrect diagnosis. Authors present a review of FNAC-induced changes with differential diagnostic criteria helpful in these pitfalls. FNAC-induced changes can be schematically divided finto two major groups - recent ones (intranodal bleeding and/or necrosis) and subacute/late ones (proliferation of granulation tissue with predominance of myofibroblasts or endothelial cells, resorptive pseudogantomathous granulomas, formation of sarcoid-like granulomas, capsular pseudoinvasion and scarring).Pathologists should be informed about the previously performed FNAC and must be aware of these lesions to prevent their misinterpretation.

Key words:
thyroid gland - fine needle aspiration cytology - postaspiration changes - necrosis - myofibroblast - sarcoid-like granuloma

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Labels
Anatomical pathology Forensic medical examiner Toxicology
Topics Journals
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