Melanoma of the female urethra

Czech version

Authors: Rodrigo Gouveia ¹; David Cibula ²; Viktor Soukup ¹; Tomáš Hanuš ¹
Authors‘ workplace: Urologická klinika, Všeobecná fakultní nemocnice a 1. LF UK v Praze ¹; Gynekologicko‑Porodnická klinika, Všeobecná fakultní nemocnice a 1. LF UK v Praze ²
Published in: Ces Urol 2019; 23(2): 149-154
Category: Case report

Overview

Melanoma of the urethra, or melanomas originating from the gynecological tract, are extremely rare and aggressive malignant tumors, with high metastatic potential and a poor prognosis, affecting almost exclusively elder female patients. The aim of this case report is to present the case of a patient with urethral and bladder melanoma metastasis from a previously treated primary melanoma of the vulva. Radical cystourethrectomy and Bricker-Nesbit ureteroileostomy and bilateral extended pelvic lymphadenectomy were performed. Histology report confirmed melanoma invading the urethra and bladder, all removed lymphatic nodes were negative. On the 6-month follow‑up PET‑CT there was no evidence of residual disease. We concluded that in the presence of such a suspicious urethral lesion, prompt diagnosis to differentiate from other benign lesions and early radical management with careful post‑operative follow‑up schedules should be the standard treatment.

Keywords:

Malignant melanoma of the urethra – metastatic melanoma of the vulva – radical cystourethrectomy

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