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Thromboembolism events in the newborn child from the point of view of present medicine


Authors: M. Grešíková
Authors‘ workplace: Klinika detskej hematológie a onkológie, Detská fakultná nemocnica s poliklinikou, Bratislava prednosta doc. MUDr. E. Kaiserová, CSc.
Published in: Čes-slov Pediat 2011; 66 (5): 299-307.
Category: Review

Overview

The incidence of thrombosis in childhood is very low in comparison to the adult population. Venous and arterial thromboses are rare diseases, being increasingly recognised and diagnosed not only in infants but also in newborns and premature newborns. Newborns, particularly the premature ones, are rather predisposed to bleeding complications due to the special properties of haemostatic system. Therefore every thrombotic event is a potentially serious condition which requires adequate diagnostic and therapeutic approach. It is very probable that most thromboembolic events occur in children, which have certain prothrombotic risk or may have met it. Acquired risk factors such as central vascular approaches, sepsis, perinatal infection and congenital heart defects are applied more frequently than congenital thrombophilic factors, with a smaller population incidence.

The following article describes the causes, clinical presentation and current management of thrombosis in neonates focusing on the clinically most relevant conditions.

Key words:
thrombosis, neonate, antitrombotic treatment


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