#PAGE_PARAMS# #ADS_HEAD_SCRIPTS# #MICRODATA#

Extramammary Vulvar Paget’s Disease – Case Report


Authors: I. Tatarková;  P. Cetkovská;  K. Pizinger
Authors‘ workplace: Dermatovenerologická klinika LF UK a FN, Plzeň přednosta prof. MUDr. Karel Pizinger, CSc.
Published in: Čes-slov Derm, 87, 2012, No. 2, p. 53-55
Category: Case Reports

Overview

Extramammary Paget’s disease (EPD) represents an uncommon carcinoma that occurs mainly in the postmenopausal Caucasian women. Apocrine gland-bearing areas are predominantly affected. The condition tends to occur as a slowly growing, invasive or noninvasive, mostly pruritic, lesion. In 25% EPD is associated with underlying internal malignancies mostly genitourinary, gastrointestinal or breast carcinoma. Vulvar Paget’s disease accounts for less than 1% of all vulvar malignancies. In our case the diagnosis of this rare carcinoma was delayed for 6 years.

Key words:
extramammary Paget’s disease


Sources

1. COTRAN, R. S., KUMAR, V., COLLINS, T., ROBBINS, S. L. Robbins Pathologic Basis of Disease. 6th Ed. Philadelphia, 1999, p. 1044–1045.

2. GREEN, J. S., BURKEMPER, N. M., FOSKO, S. W. Failure of extensive extramammary Paget disease of the inguinal area to clear with imiquimod cream, 5%: possible progression to invasive disease during therapy. Arch Dermatol, 2011, 147 (6), p. 704–708.

3. KLAPSINOU, E., TERZAKIS, E., ARNOGIANNAKI, N., DASKALOPOULOU, D. Paget’s disease of the vulva detected in vulvar and vaginal brushings mears: a case report. Acta Cytol., 2010, 54 (5), p. 898–902.

4. MADNANI, N. A., BHALERAO-GANDHI, A., KHAN, K. J. Vulvar pruritus for one year. Dermatology online journal, 2010, 16 (10): 10.

5. PARKER, L. P., PARKER, J. R., BODURKA-BEVERS, D. et al. Paget’s disease of the vulva: pathology, pattern of involvement, and prognosis. Gynecol. Oncol., 2000, 77 (1), p. 183–189.

6. PIURA, B., RABINOVICH, A., DGANI, R. Extramammary Paget’s disease of the vulva: report of five cases and review of the literature. Eur. J. Gynaecol. Oncol., 1999, 20, 2, p. 98–101.

7. PNG, J. C., TUNG, K. H., WONG, Y. E., MOKAL, N., RAJAGOPALAN, R., CHONG, P. Y. Extramammary Paget’s disease: a report of three cases and review of the literature. Ann. Acad. Med. Singapore, 1995, 24 (4), p. 636–639.

8. RAO, R. V., HENRY, D. H. Extramammary Paget’s disease. Commun. Oncol., 2004, 1 (2), p. 109–115.

9. RÜTTEN, A. Adnexaltumors. In Burgdorf, W. H. C., Plewig, G., Wolff, H. H., Landthaler, M. Braun-Falco’s Dermatology. Springer, 3rd Ed., 2009, p. 1377–1396.

10. SIMON, S. K., BOLANCA, I. K., SENTIJA, K., KUKURA, V., VALETIC, J., SKRTIC, J. Vulvar Paget’s disease – a case report. Coll. Antropol., 2010, 34 (2), p. 649–652.

11. ŠTORK, J. et al. Dermatovenerologie. Praha: Galén Karolinum, 2008, s. 171–172.

12. VANTUCHOVÁ, Y. Extramamární Pagetova choroba anogenitální oblasti. In Benáková, N. et al. Dermatologie v kazuistikách. Praha: Mladá fronta, 2008, s. 63–67.

13. WEEDON, D. Skin pathology. Churchill-Livingstone, 3rd Ed., 2010, p. 788–790.

14. WILKINSON, E. J., BROWN, H. M. Vulvar Paget disease of urothelialorigin: a report of three cases and a proposed classification of vulvar Paget disease. Hum. Pathol., 2002, 33 (5), p. 549–554.

15. ZHU, Y., YE, D. W., CHEN, Z. W., ZHANG, S. L., OIN, X. J. Frozen section – guided wide local excision in the treatment of penoscrotal extramammary Paget’s disease. BJU Int., 2007, 100 (6), p. 1282–1287.

16. ZOLLO, J. D., ZEITOUNI, N. C. The Roswell Park Cancer Institute experience with extramammary Paget’s disease. Br. J. Dermatol., 2000, 142 (1), p. 59–65.

17. MEDSCAPE REFERENCE. Extramammary Paget’s disease. [online], last updated Oct. 20.2011 [cit. 2011-7-5]URL:

<http://emedicine.medscape.com/article/1100397-overview>.

Labels
Dermatology & STDs Paediatric dermatology & STDs
Topics Journals
Login
Forgotten password

Enter the email address that you registered with. We will send you instructions on how to set a new password.

Login

Don‘t have an account?  Create new account

#ADS_BOTTOM_SCRIPTS#