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COVID-19, vaccination against SARS-CoV-2 and antiviral treatment in rheumatic diseases - revised opinion of the Czech Society for Rheumatology


Authors: Šenolt Ladislav;  Kolektiv Výboru České Revmatologické Společnosti
Authors‘ workplace: Revmatologický ústav Praha
Published in: Čes. Revmatol., 30, 2022, No. 1, p. 9-18.
Category: Recomendation

Overview

COVID-19 is an acute respiratory disease caused by a new type of coronavirus SARS-CoV-2, which can be asymptomatic or life-threatening with multiorgan failure. Patients with systemic and inflammatory rheumatic diseases generally have an increased risk of infectious complications, which is influenced not only by the severity of the immune-related disease but also by specific immunomodulatory and immunosuppressive treatments. As the number of new findings increases exponentially in the context of SARS-CoV-2 infection, some of which are contradictory, the Czech Society for Rheumatology (ČRS) decided to update the original opinion on COVID-19 in rheumatic diseases based on recent literature as well as international scientific recommendations. The risk of infection and the prognosis of COVID-19 in rheumatic patients, the effect of antirheumatic treatment on the course of COVID-19, the latest findings on the efficacy and safety of vaccination against SARS-CoV-2, including an updated opinion on vaccination timing and specific treatment in individuals with immune-mediated rheumatic diseases. Finally, the indication of antiviral treatment to high-risk rheumatic patients is also discussed.

Keywords:

infections – vaccination – glucocorticoids – SARS-CoV-2 – COVID-19 – disease-modifying treatment – inflammatory and systemic rheumatic diseases


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