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Sine syndromes in clinical picture of dermatomyositis


Authors: J. Rovenský 1;  M. Vašáková 2
Authors‘ workplace: Národný ústav reumatických chorôb Piešťany 1;  Pneumologická klinika 1. LF UK, Fakultní Thomayerova nemocnice s poliklinikou, Praha 2
Published in: Čes. Revmatol., 19, 2011, No. 1, p. 11-16.
Category: Reviews

Overview

This work deals with the issue of sine syndromes in the clinical picture of dermatomyositis. It provides a literature overview of the aforementioned sine syndromes, which is characterized by not fulfilling the diagnostic criteria for dermatomyositis; however, this disease may have a severe course. In the presented case report, we have described the development of acute interstitial pneumonia in systemic polymyositis without clinical signs of muscular involvement, with anti-Jo 1 positivity and elevated levels of myoglobin and troponin. EMG examination did not confirm any disorder in terms of myositis or neuromuscular transmission. This case report points out the necessity of examination of rheumatologic, immunological and interstitial lung involvement in cases of sine syndrome. The efficacy of glucocorticoid therapy is pointed out as well.

Key words:
dermatomyositis, sine syndromes, interstitial lung involvement, rheumatologic and immunological examination


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Dermatology & STDs Paediatric rheumatology Rheumatology
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