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Hormonal Contraception Possible Interactions


Authors: K. Hurt;  J. Šottner;  J. Záhumenský;  M. Halaška;  M. Krčmář;  A. Krajcová
Authors‘ workplace: Halaška, DrSc. ;  Gynekologicko-porodnická klinika 1. LF UK, Nemocnice na Bulovce, Praha, přednosta prof. MUDr. M.
Published in: Ceska Gynekol 2006; 71(6): 499-501
Category: Original Article

Overview

Objective:
The purpose of this article is to discuss the probable ways of interactions between some drugs or remedies and steroid contraceptives.

Design:
A review article.

Setting:
OBGYN Clinic of the 1st Faculty of Medicine, Prague, Teaching Hospital Bulovka.

Subject:
Low dose oral contraceptives are very popular these days. Some drugs and remedies could negatively influence the levels of ethinyl estradiol (EE) and/or progestins and thus increase the possibility of their failure. These drugs mostly implicate as an inducer of the CYP450 system (liver) and as an inducer of P-glycoprotein transport system (transmembrane drug pump in the intestines). We wanted to describe briefly the mechanism and the principles of their impact.

Key words:
oral contraceptives, interaction, drug, hormones, steroids


Labels
Paediatric gynaecology Gynaecology and obstetrics Reproduction medicine

Article was published in

Czech Gynaecology

Issue 6

2006 Issue 6

Most read in this issue
Topics Journals
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