Papilloma Virus Infection of the Uterine Cervix inWomen Using Contraception

Overview

Objective:
The authors analyze the prevalence of the anogenital form of HPV infection as one ofthe most frequent STD, in the female population using different types of contraception.Methods: Using the method of DNA hybridization, the authors examined for HPV infection of theuterine cervix 245 users of contraception, incl. 127 women using hormonal contraception and 118women with IUD. 112 women of this group were examined before they started to use contracepti-on and one year after started to use it. The control group was formed by 143 using no contracepti-on.Results: The authors found a significantly higher incidence of HPV infection of the uterine cervixin the group of women using contraception (24.1%) than in the control group (15.4%). On analysisof the group of women using contraception, as compared with the control group, they founda significantly higher incidence of HPV in women with hormonal contraception (26.0%) while thehigher prevalence of HPV (by 6.6%) in women with IUD as compared with the control group wasnot significant. However the differences in the incidence of HPV (4%) between the two groups ofwomen taking hormonal preparations (26.0%) or having a IUD (22%) were not significant. Onexamination of women before the onset of contraception and after one year of its use the authorsfound that candidates of contraception had as compared with the control group an insignificantly(by 3.3%) higher prevalence of HPV already before the begining of contraception. After one yearof contraception it increased by another 3.6%.Conclusion: With regard to the higher incidence of HPV in women using contraception and withregard to the oncogenic effect of HPV the authors emphasize the importance of regular detailedgynaecological examinations of these women focused on early diagnosis of precancerous conditi-ons of the uterine cervix.

Key words:
HPV, STD, contraception.