Studium obsahových látek kořenu a nati Smallanthus sonchifolius pomocí plynové chromatografie – hmotnostní spektrometrie
Authors:
Olga V. Demeshko 1; Elena V. Krivoruchko 1; Victoria A. Samoilova 1; Svetlana V. Romanova 2
Authors‘ workplace:
National University of Pharmacy, Department of Pharmacognosy
1; National University of Pharmacy, Department of Botany
2
Published in:
Čes. slov. Farm., 2018; 67, 160-163
Category:
Short News
Overview
Smallanthus sonchifolius (jakon) je nová perspektivní rostlina, která se v Evropě pěstuje jako přírodní náhražka cukrové třtiny. Používá se při diabetu a pro prevenci obezity. Studie karboxylových kyselin v kořenu a nati S. sonchifolius byla metodou plynové chromatografie – hmotnostní spektrometrie (GC-MS) provedena poprvé. Výsledkem studie bylo zjištění 12 složek v kořenu S. sonchifolius, z nichž devět byly karboxylové kyseliny. Nať S. sonchifolius obsahovala 41 složek, z nichž 18 byly karboxylové kyseliny. Dominantní sloučeniny v kořenu byly methylester kyseliny undecylové – 546,04 mg/kg; L-benzaziren-l-karboxylová kyselina, 2,2,5a-trimethyl-la-[3-oxo-l-butenyl] perhydro-methylester – 360,63 mg/kg; methylester kyseliny olejové – 119,21 mg/kg. V nati jakonu byl dominantní cyklohexanol, 1-ethinyl – 28,67 mg/kg.
Klíčová slova:
Smallanthus sonchifolius (jakon) • karboxylové kyseliny • GC-MS
Sources
1. Isaev J. I., Mykchailenko О. О., Kovalyov V. M., Gurbanov G. M., Suleymanov M. Y. Gas chromatography-mass spectrometry studies of the component composition of carboxylic acids of the rhizomes of Iris medwedewii and Iris carthaliniae (Iridaceae). Ces. Slov. Farm. 2017; 66(1), 9–14.
2. Sousa S., Pinto J., Rodrigues C., Gião M., Pereira C., Tavaria F., Malcata F. X., Gomes A., Pacheco M. T. B., Pintado M. Antioxidant properties of sterilized yacon (Smallanthus sonchifolius) tuber flour. Food Chemistry 2015; 188, 504–509.
3. Mischenko L. T. Introduction of a new medicinal plant in Ukraine. Bulletin of Agrarian Science 2012; 8, 45–48.
4. Mischenko L. T. New vegetable and medicinal crop in Ukraine. Scientific Bulletin of the National University of Bioresources and Nature Management 2012; 180, 250–256 (Series: Agronomy).
5. Ahmad Faris A. I., Dani Sugeng P., Arifah M., Nurcesuma A., Nabaatin I. Effectiveness of Yakon (Smallanthus Sonchifolius) Leaves Steeping as Insulin Subtitute for Diabetes Mellitus in Streptozotocin-Induced Diabetic Rats. International Journal of Health and Economic Development 2016; 2(1), 29–39.
6. Miura T. Antidiabetic activity of Fuscoporia oblique and Smallanthus sonchifolius in genetically tyre 2 diabetic mice. Journal of Traditional Medicines (Japan) 2007; 24(2), 47–50.
7. Baroni S., Suzuki-Kemmelmeier F., Caparroz-Assef S. M., Cuman R. K. N., Bersani-Amado C. A. Effect of crude extracts of leaves of Smallanthus sonchifolius (yacon) on glycemia in diabetic rats. Braz. J. Pharm. Sci. 2008; 44(3), 521–530.
8. Dou D. Q., Kang T. G., Qiu Y.K., Tian F. Studies on the Anti-diabetic Constituents of the Leaves of Smallanthus sonchifolius (Yacon). Planta Med. 2008; 74, 71.
9. Baroni S., da Rocha B. A., Oliveira de Melo J., Comar J. F., Caparroz-Assef S. M., Bersani-Amado C. A. Hydroethanolic extract of Smallanthus sonchifolius leaves improves hyperglycemia of streptozotocin induced neonatal diabetic rats. Asian Pac. J. Trop. Med. 2016; 9(5), 432–436.
10. Sousa S., Pinto J., Rodrigues C., Gião M., Pereira C., Tavaria F., Malcata F. X., Gomes A., Bertoldo Pacheco M. T., Pintado M. Antioxidant properties of sterilized yacon (Smallanthus sonchifolius) tuber flour. Food Chem. 2015; 188, 504–509.
11. Sousa S., Pinto J., Pereira С., Malcata F. X., Bertoldo Pacheco M. T., Gomes A. M., Pintado M. In vitro evaluation of yacon (Smallanthus sonchifolius) tuber flour prebiotic potential. Food and Bioproducts Processing 2015; 95, 96–105.
12. Mensink R. P., Zock P. L., Kester A. D., Katan M. B. Effects of dietary fatty acids and carbohydrates on the ratio of serum total to HDL cholesterol and on serum lipids and apolipoproteins: a meta-analysis of 60 controlled trials. Am. J. Clin. Nutr. 2003; 77(5), 1146–1155.
13. Choque Delgado G. T., Thomé R., Gabriel D. L., Tamashiro W. M. S. C., Pastore G. M. Yacon (Smallanthus sonchifolius)-derived fructooligosaccharides improves the immune parameters in the mous. Nutrition Research 2012; 32(11), 884–892.
14. NIST Mass Spec Data Center SES. 2005a. Mass Spectra, 6th edn. National Institute of Standards and Technology: Gaithersburg MD.
15. NIST Mass Spec Data Center SES. 2005b. Retention Indices, 6th edn.
16. State Pharmacopoeia of Ukraine. In 3 vols. 2nd ed. Kharkov: SE «Ukrainian scientific pharmacopoeial center of medicines quality». 2015; 1 (in Ukrainian).
17. Carrapiso A. I., Garcia C. Development in lipid analysis: some new extraction techniques and in situ transesterification. Lipids 2000; 35(11), 1167–1177.
18. Bicchi C., Brunelli C., Cordero C., Rubiolo P. Galli M., Sironi A. Direct resistively heated column gas chromatography (Ultrafast module-GC) for high-speed analysis of essential oils of differing complexities. J. Chromatogr. A. 2004; 1024(1–2), 195–207.
Labels
Pharmacy Clinical pharmacologyArticle was published in
Czech and Slovak Pharmacy
2018 Issue 4
Most read in this issue
- Biologická role mědi jako základního stopového prvku v lidském organismu
- Studium obsahových látek kořenu a nati Smallanthus sonchifolius pomocí plynové chromatografie – hmotnostní spektrometrie
- Studie vlivu derivátu 1,3-oxazol-4-yl-fosfonové kyseliny na systémové indikátory aktivity oxidu dusnatého u potkanů s arteriální hypertenzí