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Applications of molecularly imprinted polymers in analytical and pharmaceutical chemistry


Authors: M. Lachová 1;  J. Lehotay 1;  J. Čižmárik 2
Authors‘ workplace: Institute of Analytical Chemistry, Faculty of Chemical and Food Technology, Slovak University of Technology, Bratislava, Slovak Republic 1;  Department of Pharmaceutical Chemistry, Faculty of Pharmacy, Comenius University, Bratislava Slovak Republic 2
Published in: Čes. slov. Farm., 2007; 56, 159-164
Category: Review Articles

Overview

The paper reviews recent developments in the use of molecularly imprinted polymers in several analytical techniques, such as solid-phase extraction, liquid chromatography, capillary electrophoresis, capillary electrochromatography, and as selective sorbents in chemical sensors. Molecular imprinting is achieved by the interaction between complementary groups in a template molecule and functional monomer units. The benefits of imprinted polymers are low cost, storage stability, high mechanical strength, repeated operations without loss of activity, and potential application to a wide range of target molecules.

Key words:
molecularly imprinted polymers – solid-phase extraction – liquid chromatography – electrochromatography – membranes – sensors


Labels
Pharmacy Clinical pharmacology
Topics Journals
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