Findings on Optical Coherence Tomography in Macular Degeneration with PredominantlyClassic Subfoveal Choroidal Neovascularization Treated by PhotodynamicTherapy with Visudyne

Overview

We determined findings on optical coherence tomography (OCT) in maculardegeneration with predominantly classic subfoveal choroidal neovascularizationtreated by photodynamic therapy (PDT) with Visudyne.We performed 21correlations of central retinal thickness (CRT) on OCT2 withfindings on fluorescein angiography (FA) in our study.We quantifiedCRTonOCT2in 14 cases before, during and after the end of the treatment. The control groupwas composed from patients, who were not able to undergo the treatment andtherefore it was postponed.CRT on OCT correlated with FA in 95 % of cases in our study. Maximal decrease of CRT is demonstrated during the first three months oftreatment. Values of CRT on OCT are in patients after repeated sessions of PDTlower than before the first session. These values can grow up a little for some timedue to increase of amount of intraretinal fluid during the first week after thesession of PDT. During next follow-up there are no big differences between valuesof CRT. In the control group CRT on OCT increases progressively during thefollow-up.

Key words:
macular degeneration, photodynamic therapy, fluorescein angiography,optical coherence tomography