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Duo-Bonharen - a New Viscoelastic Preparation


Authors: A. Al-Farzai *;  J. Novák **;  F. Hubálek ***;  P. Češková ***;  J. Kvasnička *;  F. Langr ****
Authors‘ workplace: Oční klinika, Fakultní Nemocnice a Lékařská fakulta v Hradci Králové Univerzity Karlovy v Praze, přednosta prof. MUDr. P. Rozsíval, CSc. **Oční oddělení Krajské nemocnice Pardubice a Ústavu zdravotnických studií UniverzityPardubice, přednosta doc. MUDr. J *
Published in: Čes. a slov. Oftal., , 2003, No. 2, p. 91-97
Category:

Overview

Thepaper discusses preclinical tests of anewviscoelastic preparation forophthalmosurgery.Experiments revealed that preparationDuo-Bonharen whichcontainshyaluronic acid prepared by bacterial fermentation is suited for clinical tests.After a 24-hour interval following administration into the anterior chamber itdoes not raise intraocular pressure. In experiments it has no side-effects on theeye. The dispersed form in a higher concentration (5 %) adheres verywell to oculartissues and protects them adequately during surgery. The cohesive form in anoptimal concentration (1.5 %) can be rapidly removed from inside the eye. Theproperties of Duo-Bonharen in experiments are comparable with similar viscomaterialswhich are used. The new viscoelastic material Duo-Bonharen appearssuitable for clinical tests in particular for cataract surgery.

Key words:
hyaluronic acid, viscomaterial, microsurgery of the eye

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Ophthalmology
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