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Allergodil Eye Drops in the Treatment of Allergic Conjunctivitis


Authors: P. Haicl;  H. Černá
Authors‘ workplace: Oční klinika VFN a 1. LF UK, Praha, přednosta doc. MUDr. M. Filipec, CSc.
Published in: Čes. a slov. Oftal., , 2002, No. 4, p. 254-258
Category:

Overview

The authors describe a group of 20 patients with symptoms of allergic conjunctivitiswhere for a period of 2-6 weeks twice a day into the conjunctival sac of botheyes Allergidol gtt, ophth., ASTA Medica AG FRG was administered.As to subjective sensations the authors evaluated itching, burning, the sensationof a foreign body and lacrimation, as to objective signs oedema of the eyelids,hyperaemia of the conjunctiva and papillary hypertrophy. The authors evaluatedalso the rate of onset of the effect, its duration and tolerance of the preparation.Subjective symptoms disappeared in 90%patients,hyperaemia of the conjunctivaeand papillary hypertrophy receded in 12 patients (60%), in 8 (40%) they disappeared.Regression of subjective complaints occurred in all patients within 20 minutes,the duration of the effect was within the range of 11-13 hours in 18 patients(90%), 6-8 hours in two patients (10%). As to undesirable effects one female patientreported after administration of the eye drops a bitter sensation in the mouth,another one a burning sensation.Evidence was provided that the local H1 antihistaminic Allergodil gtt is effectivein monotherapy in mild forms of allergic conjunctivitis.

Key words:
allergic conjunctivitis local H1 antihistaminic, Allergodil, azelastin

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Ophthalmology
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