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Glycated albumin in blood serum/plasma. Brief overview of the current state.


Authors: B. Friedecký 1,2;  J. Kratochvíla 2
Authors‘ workplace: Ústav klinické biochemie a diagnostiky FN Hradec Králové, Sokolská 581, Hradec Králové 1;  SEKK s. r. o., Pardubice 2
Published in: Klin. Biochem. Metab., 26, 2018, No. 2, p. 79-81

Overview

Objective:

Minireview on the current state in measurement and interpretation of glycated albumin.

Method:

Publication is based on the current literature.

Results:

Enzymatic photometric methods for measurement of glycated albumin show good analytical quality and can be realized in routine clinical laboratories by using standard laboratory equipment.

Discussion:

Determination of glycated albumin in serum is candidate marker for management of diabetes in patients with changes of half-life erythrocytes.

Keywords:

Glycated albumin, enzymatic method, minireview, glycated haemoglobin HbA<sub>1c</sub>.


Sources

1. Guidelines and recommendations for laboratory analysis in the diagnosis and management of diabetes mellitus. Ed D.B.Sacks. NACB 2011 (dostupné na: www.aacc.org).

2. American Diabetes Association Standards of medical care in diabetes 2016. Diabetes Care 2016,39: Suppl 1.

3. Müller-Wieland, D., Petermann, A., Nauck, M., Heinemenn, W., Kerner, U., Müller, A., Landgraf, R. Definition, Klassifikation und Diagnostik des Diabetes mellitus. Diabetologie, 2016,11,Suppl 2, S78-S81.

4. Little, R. R. Usefulness of glycated albumin assay for diabetes monitoring. J Diabetes Sci. Technol., 2011, 5, p. 1463-1465.

5. Hare, M. J. L., Shaw, J. E., Zimmet, P. Z. Current controversies in the use of haemoglobin A1c. J Intern. Med., 2012, 271, p. 227-236.

6. HbA1c Interferences. Dostupné na: http://www.ngsp.org

7. Sickle Cell Trait and other hemoglobinpathies and diabetes. NIH. National Institute of Diabetes and Digestive and Kidney Disease. Dostupné na: https://www.niddk.nih.gov

8. Welsh, K. J., Kirkman, M. S., Sacks, D. B. Role of glycated proteins in the diagnosis and management of diabetes: research gaps and future directions. Diabetes Care, 2016, 39, p. 1299-1306.

9. Ueda, Y., Matsumoto, H. Recent topics in chemical and clinical research on glycated albumin. J Diabetes Sci. Technol., 2015, 9, p. 177-182.

10. Kohzuma, T., Yamamoto, T., Uematsu, Y., Shihabi, Z. K., Freedman, B. I. Basic performance of an enzymatic method for glycated albumin and reference range determination. J Diabetes Sci. Technol., 2011, 5, p. 1455-1462.

11. Testa, R., Guerra, E., Bonfigli, A. R., Di Gaetano, N., Santini, G., Cerriotti, F. Analytical performances of an enzymatic assay for the measurement of glycated albumin. J Appl. Lab. Med., 2016, 2/1, p. 162-171.

12. Paleari, R., Bonetti, G., Calla, C., Carta, M., Cerriotti, F., Di Gaetano, N. et al. Multicenter evaluation of an enzymatic method for glycated albumin. Clin. Chim. Acta, 2017, 469, p. 81-86.

13. Bellia, C., Zanimotto, M., Cosma, C., Angello, L., Lo Sasso, B., Bivona, G. et al. Definition of the upper re-ference limit of glycated albumin in blood donors in Italy. Clin. Chem. Lab. Med., 2017, 56/1, p. 120–125.

14. Montagnana, M., Paleari, R., Danese, E., Salvagno, G. L., Lippi, G., Guidi, G. C., Mosca, A. Evaluation of biological variation of glycated albumin (GA) and fructosamin in healthy subjects. Clin. Chim. Acta, 2013, 23/423, p. 1-4.

15. Reynolds, A. N., Harper, M., Venn, B. J., Mann, J. Glycated albumin is stable in plasma when exposed to common laboratory conditions and comparable when drawn from venous and capillary sites. J Clin. Lab. Anal., 2018, 32/2. doi:10.1002/jcla.22236.

16. Danese, E., Montagnana, M., Nouvenne, A., Lippi, G. Advantages and pitfalls of fructosamine and glycated albumin in the diagnosis and treatment of diabetes. J Diabetes Sci. Technol., 2015, 9, p. 169-176.

17. Testa, R., Guerra, E., Bonfigli, A. R., Boemi, M., Cucchi, M., Di Gaetano, N. et al. Glycated albumin: correlation to HbA1c and preliminary reference interval evaluation. Clin. Chem. Lab. Med., 2017, 55/2, e31-e33.

18. Takei, I., Hoshino, T., Tominaga, M., Ishibashi, M., Kuwa, K., Umemoto, M. et al. Committee on diabetes mellitus of the Japan Society of Clinical Chemistry -recommended reference measurement procedure and reference materials for glycated albumin determination. Ann. Clin. Biochem., 2016, 53, p. 124-132.

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