Treatment of sideropenic anemia in gastroenterology

Czech version

Authors: M. Lukáš
Authors‘ workplace: Klinické a výzkumné centrum pro střevní záněty ISCARE I. V. F a. s. Ústav lékařské biochemie a laboratorní diagnostiky 1. LF UK
Published in: Kardiol Rev Int Med 2014, 16(5): 370-373
Category: Cardiology Review

Overview

Gastrointestinal causes of sideropenic anemia are very common. For this reason, a specialized endoscopic examination is indicated in at least 15% of gastroenterology patients. The leading causes of anemia are drug-induced gastrointestinal ulcers (NSAID gastropathy, NSA enteropathy) and cancer. Less frequent causes include the failure of iron absorption in celiac disease or the effects of massive bleeding in the digestive tract. Patients with inflammatory bowel diseases represent a specific population, and anemia is present in 70% of them. It is usually a combination of sideropenic anemia with anemia resulting from chronic inflammation. Preparations containing iron bound in carbohydrate complexes (carboxymaltose) represent a significant advance in the treatment of intravenous sideropenic anemia. Unlike iron bound to gluconate or dextran, this new intravenous iron substitution is a highly effective and safe treatment modality.

Keywords:
sideropenic anemia – sideropenia – carboxymaltose – ferotherapy

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