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Aprotinin in cardiac surgery – re-evaluation of the risks?


Authors: T. Vaněk;  J. Hlavička;  P. Budera
Authors‘ workplace: Kardiochirurgická klinika 3. LF UK, Praha
Published in: Anest. intenziv. Med., 27, 2016, č. 5, s. 284-288
Category: Anaesthesiology - Special Article

Overview

The article describes the history of introducing aprotinin into cardio-surgical clinical practice and deals with the circumstances based on the results of the BART study leading to its withdrawal from the global pharmaceutical market and with its recent re-authorization in some countries.

KEYWORDS:
cardiac surgery – fibrinolysis – fibrinolytic inhibitors – aprotinin


Sources

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Anaesthesiology, Resuscitation and Inten Intensive Care Medicine
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