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New role and rennaisance of branched chain aminoacids in intensive care


Authors: Zadák Zdeněk;  Hyšpler Radomír;  Tichá Alena
Published in: Anest. intenziv. Med., 23, 2012, č. 5, s. 253-258
Category: Intensive Care Medicine - Review Article

Overview

The branched chain amino acids valine, leucine and isoleucine are essential nutrients with more than nutritional effects. They are important mediators and structural components in proteosynthesis and they regulate hormonal functions. Leucine is a precursor in cholesterol synthesis and as such plays an important role in muscle tissue growth and in sarcopenia suppression. Older and recent data are reviewed and support wider utilization of branched chain amino acids in intensive care.

Keywords:
branched chain amino acids – valine – leucine – izoleucine – sarcopenia – catabolism – beta-hydroxy beta-methylbutyrate – critical condition


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Labels
Anaesthesiology, Resuscitation and Inten Intensive Care Medicine
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