First Experience with New Analgesic Neodolpasse R

Overview

Treatment of a pain after thoracic surgery procedures remains a chalenge. Thoracotomy is very painful but excessively sedated patients in thepostoperative period do not cooperate, hypoventilate and do not cough enough. Postoperative complications can seriously worsen patient’s status.At Dept. of Surgery I in Olomouc in period between April–August 2001 we used a new intravenous analgetic agent Neodolpasse R (produced byFresenius Kabi) for treatment of a pain after thoracic surgery procedures.Neodolpasse R consists of two effective substances – Diclofenacum natricum and Orphenadrini citras (NSAID and central myorelaxans). Weadministered Neodolpasse R once a day for a period of four days. Analgesia was effective, well tolerated, without side effects. We followed subjectivefeeling of a pain on a scale 0–100% and we examined acid-base balance (Astrup) before and after administration of Neodolpasse R. The data werecompared and statistically analysed. Ventilation was significantly improved after administration of Neodolpasse R. Neodolpasse R widens selection ofanalgetic agents after thoracic surgery procedures.

Key words:
post-toracothomy pain, Neodolpasse R