Continuous Administration of Atracurium and Mivacurium with Neuromuscular Block Monitoring

Overview

Continuous administration of neuromuscular blocking agents allows to perform a controlled neuromuscular block. Neuromuscular monitoring withdifferent stimulation modes is a necessary prerequisite for the control of a depth block. This technique of administration appears to be attractive incases when profound relaxation of muscles is desired until the end of surgery, then rapid recovery should follow. Laparoscopic procedures are typicalcases. The neuromuscular blocking agents mivacurium and atracurium fulfill the criteria for minimal accumulation in the organism, both agents allowfor rapid recovery of neuromuscular function. Recovery time can be shortened by antagonizing the block.

Key words:
administration by infusion – neuromuscular block monitoring – neuromuscular strength monitoring – controlled relaxation